AH-7921 = Doxylam; 1-(3,4-dichlorobenzamidomethyl)cyclohexyldimethylamine Minimal oral effective doses for complete pain suppression by AH 7921 are 1.25 and 13.8 mg/kg
It’s an N-substituted cyclohexylmethylbenzamide. The “AH” refers to Allen & Hanburys, which originally patented the
AH-7921 is a derivative of dimethylaminocyclohexane, with the addition of a 3,4-dichlorobenzamide moiety.
AH-7921 is primarily metabolized to desmethyl-AH-7921, which can then result in di-desmethyl-AH-7921
The drug is often taken orally, though there are reports of intranasal, sublingual, IV, and rectal administration.
Total: 6 – 8 hours (some reports indicate around 4 – 5 hours)
Onset: 00:15 – 00:45
Total: 3 – 4 hours
Onset: 00:02 – 00:10